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Aliskiren inhibits renin-mediated complement activation

Head-to-head comparison of the new calcimimetic agent evocalcet with cinacalcet in Japanese hemodialysis patients with secondary hyperparathyroidism

TACI deletion protects against progressive murine lupus nephritis induced by BAFF overexpression

A prospective observational cohort study highlights kidney biopsy findings of lupus nephritis patients in remission who flare following withdrawal of maintenance therapy
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    New article type now available in Kidney International!

    We are pleased to announce that Kidney International will now accept Brief Reports. The purpose of the Brief Report format is to publish concise but complete reports that present high-quality findings of exceptional interest, novelty, and broad significance for the readers of Kidney International. Click here to review the author instructions for Brief Reports. We look forward to receiving your submissions!

      • CD8+ T cells modulate autosomal dominant polycystic kidney disease progression

        Emily K. Kleczko, Kenneth H. Marsh, Logan C. Tyler, Seth B. Furgeson, Bonnie L. Bullock, Christopher J. Altmann, Makoto Miyazaki, Berenice Y. Gitomer, Peter C. Harris, Mary C.M. Weiser-Evans, Michel B. Chonchol, Eric T. Clambey, Raphael A. Nemenoff, Katharina Hopp
        DOI: https://doi.org/10.1016/j.kint.2018.06.025
        Publication stage: In Press Corrected Proof
        Kidney International
        Open Access
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      • Iron attenuates erythropoietin production by decreasing hypoxia-inducible transcription factor 2α concentrations in renal interstitial fibroblasts

        Norio Suzuki, Yukari Matsuo-Tezuka, Yusuke Sasaki, Koji Sato, Kenichiro Miyauchi, Koichiro Kato, Sakae Saito, Yasushi Shimonaka, Michinori Hirata, Masayuki Yamamoto
        DOI: https://doi.org/10.1016/j.kint.2018.06.028
        Publication stage: In Press Corrected Proof
        Kidney International
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      • Rictor deficiency in dendritic cells exacerbates acute kidney injury

        Helong Dai, Alicia R. Watson, Daniel Fantus, Longkai Peng, Angus W. Thomson, Natasha M. Rogers
        DOI: https://doi.org/10.1016/j.kint.2018.06.010
        Publication stage: In Press Corrected Proof
        Kidney International
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      • The angiotensin II type 2 receptors protect renal tubule mitochondria in early stages of diabetes mellitus

        Tamara Micakovic, Stamatia Papagiannarou, Euan Clark, Yalcin Kuzay, Katarina Abramovic, Jörg Peters, Carsten Sticht, Nadine Volk, Thomas Fleming, Peter Nawroth, Hans-Peter Hammes, Natalia Alenina, Hermann-Josef Gröne, Sigrid Christa Hoffmann
        DOI: https://doi.org/10.1016/j.kint.2018.06.006
        Publication stage: In Press Corrected Proof
        Kidney International
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      • HIF-1α promotes cyst progression in a mouse model of autosomal dominant polycystic kidney disease

        Andre Kraus, Dorien J.M. Peters, Bernd Klanke, Alexander Weidemann, Carsten Willam, Gunnar Schley, Karl Kunzelmann, Kai-Uwe Eckardt, Bjoern Buchholz
        DOI: https://doi.org/10.1016/j.kint.2018.06.008
        Publication stage: In Press Corrected Proof
        Kidney International
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    • Age- and gender-specific reference values of estimated GFR in Caucasians: The Nijmegen Biomedical Study

      J.F.M. Wetzels, L.A.L.M. Kiemeney, D.W. Swinkels, H.L. Willems, M.den Heijer
      DOI: https://doi.org/10.1038/sj.ki.5002374
      Kidney International, Vol. 72, Issue 5, p632–637
      Open Archive
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    • Executive summary of the 2018 KDIGO Hepatitis C in CKD Guideline: welcoming advances in evaluation and management

      Michel Jadoul, Marina C. Berenguer, Wahid Doss, Fabrizio Fabrizi, Jacques Izopet, Vivekanand Jha, Nassim Kamar, Bertram L. Kasiske, Ching-Lung Lai, José M. Morales, Priti R. Patel, Stanislas Pol, Marcelo O. Silva, Ethan M. Balk, Craig E. Gordon, Amy Earley, Mengyang Di, Paul Martin
      DOI: https://doi.org/10.1016/j.kint.2018.06.011
      Kidney International, Vol. 94, Issue 4, p663–673
      Open Access
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    • Assessment of intravascular volume status and volume responsiveness in critically ill patients

      Kambiz Kalantari, Jamison N. Chang, Claudio Ronco, Mitchell H. Rosner
      DOI: https://doi.org/10.1038/ki.2012.424
      Kidney International, Vol. 83, Issue 6, p1017–1028
      Open Archive
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    • Long-term kidney outcomes among users of proton pump inhibitors without intervening acute kidney injury

      Yan Xie, Benjamin Bowe, Tingting Li, Hong Xian, Yan Yan, Ziyad Al-Aly
      DOI: https://doi.org/10.1016/j.kint.2016.12.021
      Kidney International, Vol. 91, Issue 6, p1482–1494
      Open Access
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    • Pathogenesis and treatment of dialysis hypotension

      W. Sulowicz, A. Radziszewski
      DOI: https://doi.org/10.1038/sj.ki.5001975
      Kidney International, Vol. 70, S36–S39
      Open Archive
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    Nobel Prize for Medicine 2016 awarded to Professor Ohsumi of Japan for his discovery of the molecular and cell biological pathways of autophagy.

    Autophagy has been shown to be an essential mechanism by which cells remove defective molecular and cell organelle components, thereby renewing themselves constantly and especially after cell injury. Dysfunction of this pathway has since been shown to be important in the development of many acute and chronic degenerative diseases, including AKI and CKD. This has been reviewed recently in KI,

    Autophagy in Acute Kidney Injury by Kaushal and Shah
    Autophagy in Kidney Disease and Aging: Lessons from Rodent Models by Lenoir, Tharaux, and Huber.

    and continues to be at the forefront of research directed at the pathophysiology and potential novel avenues of therapeutic interventions for kidney diseases.

    With the January 2016 issue, Elsevier will be the official publisher of Kidney International, an official publication of the International Society of Nephrology. Read the full press release.

    I am delighted that ISN managed to find a great publisher in Elsevier. Considering the big changes happening in the field of medical publishing, it is very reassuring that Kidney International is such an attractive journal to Elsevier. ISN is proud to have such an important pillar to its leading Global Education portfolio, currently delivering tailored education to a broad range of kidney professionals worldwide, through publications, meetings and a content-rich online portal.

    David Harris, ISN Global Education Director


    About KI

    Kidney International (KI) is the official journal of the International Society of Nephrology. Under the editorial leadership of Dr. Pierre Ronco (Paris, France), KI is one of the most cited journals in nephrology and widely regarded as the world's premier journal on the development and consequences of kidney disease.

    KI is peer-reviewed and publishes original research in both basic science and clinical medicine. These include the latest clinical studies on emerging developments in renal medicine and the highest level of original research studies in therapy and epidemiology of acute and chronic kidney failure, as well as their translational aspects and genetic basis. In addition relevant aspects of renal physiology, cell biology, biochemistry, pathology, immunology, morphology and new technological developments are reported with the over-all aim of informing the renal researcher and the practicing nephrologist on all aspects of renal research.

    The journal reflects the field through critical reviews and original articles, commentaries, editorial updates on recent developments and news features, recommendations and guidelines resulting from expert consensus meetings, aspects of nephrology from the developing world, policy issues, remarkable images, and problem-focused articles for the diagnosis and treatment of renal patients. Kidney International is published monthly.
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    About the International Society of Nephrology

    ISN

    The International Society of Nephrology (ISN) is advancing kidney care worldwide. Through our scientific and capacity-building activities in advocacy, education and research, we bridge gaps in global kidney care, engaging in a collaborative effort to improve kidney disease prevention, diagnosis and treatment.

    With over 9,000 professional members from over 150 countries, the ISN represents a wide international network and an efficient platform for timely scientific exchange, debate and communication between healthcare professionals involved in preventing and treating kidney disease.

    By collaborating with more than 100 national and regional societies, we reach out to an additional 30,000 health professionals globally. Our overarching purpose is to tackle the global burden of Acute Kidney Injury (AKI) and Chronic Kidney Disease (CKD), improving patient care through an interconnected advocacy, education and research strategy.

    Current Issue

    Cover image volume 94, Issue 4
    October 2018
    Volume 94, Issue 4
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    8.429
    2017
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    4/76
    Urology &
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    Supports Open Access


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    KI Supplements

    Our companion journal, KI Supplements, focuses on sponsored, topical content of interest to the nephrology community. The journal is complimentary to KI subscribers.

    2016 Impact Factor is 5.593

    KI Reports

    Our companion journal, KI Reports, is a peer reviewed, open access journal devoted to the publication of leading research and developments related to kidney disease.

    Submit your article today!